Mvp Polyclonal Antibody for Rat(Rattus norvegicus) | EIAab.comMvp Polyclonal Antibody for Rat(Rattus norvegicus)

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Mvp (Gene name),

Major vault protein (Protein name ), MVP_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Mvp;

Protein name:

Major vault protein(MVP);

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

The vault ribonucleoprotein particle is a huge (400 A x 670 A) cage structure of 12.9 MDa. It consists of a dimer of half-vaults, with each half-vault comprising 39 identical major vault protein (MVP) chains, PARP4 and one or more vault RNAs (vRNAs). Interacts with TEP1. Interacts with PTEN and activated MAPK1. The phosphorylated protein interacts with the SH2 domains of PTPN11 and SRC. Interacts with APEX1 (By similarity). May interact with ZNF540.

Function:

Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

Subcellular Location:

Cytoplasm Nucleus

Protein Attributes:

Sequence length:

861

Sequence:

50:

100:

150:

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250:

300:

350:

400:

450:

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650:

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750:

800:

850:

861:

LGSDGQPPAQ | K

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q62667

Pfam:

PF11978

KEGG:

rno:64681

UniGene:

Rn.10028

SMR:

Q62667

STRING:

10116.ENSRNOP00000027360

Uniprot:

Q62667

FOR

ELISA Kit for Rat MVP

Cat.:

E1071h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Rat MVP

Cat.:

E1071m

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Rat MVP

Cat.:

E1071b

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MSDS:

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Packing:

96T

ELISA Kit for Rat MVP

Cat.:

E1071r

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MSDS:

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Packing:

96T

ELISA Kit for Rat MVP

Cat.:

E1071c

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MSDS:

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Packing:

96T

CLIA Kit for Rat MVP

Cat.:

U1071b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat MVP

Cat.:

U1071r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat MVP

Cat.:

U1071h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Rat MVP

Cat.:

U1071c

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat MVP

Cat.:

U1071m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat MVP

Cat.:

P1071Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat MVP

Cat.:

P1071Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat MVP

Cat.:

P1071Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat MVP

Monoclonal Antibody for Rat MVP

Protein for Rat MVP

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The sequence of a cDNA encoding the major vault protein from Rattus norvegicus."
Kickhoefer V.A. , Rome L.H.
Gene151:257-260(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

Kickhoefer V.A.
Submitted (2004-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO C-TERMINUS
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.
4.

"Vaults and telomerase share a common subunit, TEP1."
Kickhoefer V.A. , Stephen A.G. , Harrington L. , Robinson M.O. , Rome L.H.
J. Biol. Chem.274:32712-32717(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ASSOCIATION WITH TEP1
5.

"Draft crystal structure of the vault shell at 9-A resolution."
Anderson D.H. , Kickhoefer V.A. , Sievers S.A. , Rome L.H. , Eisenberg D.
PLoS Biol.5:E318-E318(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (9.0 ANGSTROMS);SUBUNIT
6.

"The structure of rat liver vault at 3.5 Angstrom resolution."
Tanaka H. , Kato K. , Yamashita E. , Sumizawa T. , Zhou Y. , Yao M. , Iwasaki K. , Yoshimura M. , Tsukihara T.
Science323:384-388(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS);SUBUNIT;MVP REPEATS

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